Cross-species transplant in rhesus macaques
October 28th 2007 10:55
Cross-species transplant in rhesus macaques is step toward diabetes cure for humans
Oct. 18, 2007 --
Hammerman
Hammerman
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In a new study with an eye on curing diabetes, senior investigator Marc Hammerman and a group of WUSM scientists successfully transplanted embryonic pig pancreatic cells destined to produce insulin into diabetic macaque monkeys - all without the need for risky immune suppression drugs that prevent rejection. The transplanted cells, known as primordia, are in the earliest stages of developing into pancreatic tissues. Within several weeks of the transplants, the cells became engrafted, or established, within the three rhesus macaque monkeys that received them. The cells also released pig insulin in response to rising blood glucose levels, as would be expected in healthy animals and humans.
Oct. 18, 2007 --
Hammerman
Hammerman
Download
In a new study with an eye on curing diabetes, senior investigator Marc Hammerman and a group of WUSM scientists successfully transplanted embryonic pig pancreatic cells destined to produce insulin into diabetic macaque monkeys - all without the need for risky immune suppression drugs that prevent rejection. The transplanted cells, known as primordia, are in the earliest stages of developing into pancreatic tissues. Within several weeks of the transplants, the cells became engrafted, or established, within the three rhesus macaque monkeys that received them. The cells also released pig insulin in response to rising blood glucose levels, as would be expected in healthy animals and humans.
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